G37C (p.Gly37Cys) variant of PARK7 (Parkinson disease protein 7)
G37C (p.Gly37Cys) in PARK7 (Parkinson disease protein 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data, published literature, and structural context.
G37C (p.Gly37Cys) variant details
- p.Gly37Cys
- gnomAD 1-7965342-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.736
- REVEL 0.71
- MetaLR 0.65
- MetaSVM 0.45
- CADD 28.20
- PolyPhen-2 1.00
- SIFT 0.08
- Population evidence available
- Structural context available
- Literature evidence available