A61V (p.Ala61Val) variant of PARK7 (Parkinson disease protein 7)
A61V (p.Ala61Val) in PARK7 (Parkinson disease protein 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
A61V (p.Ala61Val) variant details
- p.Ala61Val
- gnomAD rs1449957205
- Missense
- Variant Prioritization Score for Impact Estimate 0.474
- REVEL 0.28
- CADD 22.90
- PolyPhen-2 0.09
- SIFT 0.37
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available