T15I (p.Thr15Ile) variant of PADI4 (Q9UM07)
T15I (p.Thr15Ile) in PADI4 (Q9UM07) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data, published literature, and structural context.
T15I (p.Thr15Ile) variant details
- p.Thr15Ile
- gnomAD 1-17308266-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.438
- REVEL 0.28
- CADD 22.20
- PolyPhen-2 1.00
- SIFT 0.14
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available