S45T (p.Ser45Thr) variant of PADI4 (Q9UM07)
S45T (p.Ser45Thr) in PADI4 (Q9UM07) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
S45T (p.Ser45Thr) variant details
- p.Ser45Thr
- TOPMed rs2074200805
- gnomAD rs2074200805
- Missense
- Variant Prioritization Score for Impact Estimate 0.271
- REVEL 0.07
- CADD 6.96
- PolyPhen-2 0.03
- SIFT 0.75
- Most common in the Latino/Admixed American population (allele frequency 0.00013)
- Structural context available