L27P (p.Leu27Pro) variant of PADI4 (Q9UM07)
L27P (p.Leu27Pro) in PADI4 (Q9UM07) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
L27P (p.Leu27Pro) variant details
- p.Leu27Pro
- ExAC rs776068449
- TOPMed rs776068449
- gnomAD rs776068449
- Missense
- Variant Prioritization Score for Impact Estimate 0.465
- REVEL 0.34
- CADD 25.40
- PolyPhen-2 0.93
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-06)
- Structural context available