L21P (p.Leu21Pro) variant of PADI4 (Q9UM07)
L21P (p.Leu21Pro) in PADI4 (Q9UM07) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
L21P (p.Leu21Pro) variant details
- p.Leu21Pro
- 1000Genomes rs547720396
- ExAC rs547720396
- gnomAD rs547720396
- Missense
- Variant Prioritization Score for Impact Estimate 0.513
- REVEL 0.42
- CADD 26.30
- PolyPhen-2 0.93
- SIFT 0.02
- Most common in the 1KG:BEB population (allele frequency 0.0051)
- Structural context available