I7T (p.Ile7Thr) variant of PADI4 (Q9UM07)
I7T (p.Ile7Thr) in PADI4 (Q9UM07) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
I7T (p.Ile7Thr) variant details
- p.Ile7Thr
- gnomAD rs1172726333
- Missense
- Variant Prioritization Score for Impact Estimate 0.408
- REVEL 0.25
- CADD 23.80
- PolyPhen-2 0.66
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available