G22S (p.Gly22Ser) variant of PADI4 (Q9UM07)
G22S (p.Gly22Ser) in PADI4 (Q9UM07) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
G22S (p.Gly22Ser) variant details
- p.Gly22Ser
- ESP rs367980085
- ExAC rs367980085
- TOPMed rs367980085
- gnomAD rs367980085
- Missense
- Variant Prioritization Score for Impact Estimate 0.58
- REVEL 0.43
- CADD 25.70
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available