G22R (p.Gly22Arg) variant of PADI4 (Q9UM07)
G22R (p.Gly22Arg) in PADI4 (Q9UM07) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data, published literature, and structural context.
G22R (p.Gly22Arg) variant details
- p.Gly22Arg
- gnomAD 1-17308286-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.616
- REVEL 0.49
- CADD 25.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available