G22A (p.Gly22Ala) variant of PADI4 (Q9UM07)
G22A (p.Gly22Ala) in PADI4 (Q9UM07) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
G22A (p.Gly22Ala) variant details
- p.Gly22Ala
- gnomAD 1-17308287-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.419
- REVEL 0.39
- CADD 23.50
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available