Y64F (p.Tyr64Phe) variant of ORC1 (Q13415)
Y64F (p.Tyr64Phe) in ORC1 (Q13415) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data, published literature, and structural context.
Y64F (p.Tyr64Phe) variant details
- p.Tyr64Phe
- gnomAD 13-40799165-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.408
- REVEL 0.36
- CADD 19.80
- PolyPhen-2 0.00
- SIFT 0.39
- Population evidence available
- Structural context available
- Literature evidence available