Y64C (p.Tyr64Cys) variant of ORC1 (Q13415)
Y64C (p.Tyr64Cys) in ORC1 (Q13415) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.77 / 1. The record also includes population frequency data and structural context.
Y64C (p.Tyr64Cys) variant details
- p.Tyr64Cys
- ESP rs367621213
- TOPMed rs367621213
- gnomAD rs367621213
- Missense
- Variant Prioritization Score for Impact Estimate 0.768
- REVEL 0.85
- CADD 29.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available