V36G (p.Val36Gly) variant of ORC1 (Q13415)
V36G (p.Val36Gly) in ORC1 (Q13415) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.72 / 1. The record also includes population frequency data, published literature, and structural context.
V36G (p.Val36Gly) variant details
- p.Val36Gly
- gnomAD 13-40799105-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.722
- REVEL 0.86
- CADD 25.60
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available