I45V (p.Ile45Val) variant of ORC1 (Q13415)
I45V (p.Ile45Val) in ORC1 (Q13415) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
I45V (p.Ile45Val) variant details
- p.Ile45Val
- rs1156296838
- gnomAD 13-40793245-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.24
- REVEL 0.21
- CADD 6.67
- PolyPhen-2 0.00
- SIFT 0.76
- Population evidence available
- Structural context available
- Literature evidence available