G50S (p.Gly50Ser) variant of ORC1 (Q13415)
G50S (p.Gly50Ser) in ORC1 (Q13415) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data, published literature, and structural context.
G50S (p.Gly50Ser) variant details
- p.Gly50Ser
- gnomAD 13-40799137-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.503
- REVEL 0.47
- CADD 21.20
- PolyPhen-2 0.12
- SIFT 0.26
- Population evidence available
- Structural context available
- Literature evidence available