G18G (p.Gly18Gly) variant of ORC1 (Q13415)
G18G (p.Gly18Gly) in ORC1 (Q13415) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
G18G (p.Gly18Gly) variant details
- p.Gly18Gly
- gnomAD 13-40799058-A-T
- Splice Region
- Variant Prioritization Score for Impact Estimate 0.233
- CADD 11.20
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available
- Literature evidence available