V29F (p.Val29Phe) variant of NUDT15 (Q9NV35)
V29F (p.Val29Phe) in NUDT15 (Q9NV35) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
V29F (p.Val29Phe) variant details
- p.Val29Phe
- gnomAD 13-48037831-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.353
- REVEL 0.34
- MetaLR 0.11
- MetaSVM -1.03
- CADD 22.90
- PolyPhen-2 0.87
- SIFT 0.17
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available
- Literature evidence available