V20L (p.Val20Leu) variant of NUDT15 (Q9NV35)
V20L (p.Val20Leu) in NUDT15 (Q9NV35) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
V20L (p.Val20Leu) variant details
- p.Val20Leu
- TOPMed rs1950544019
- Missense
- Variant Prioritization Score for Impact Estimate 0.267
- REVEL 0.08
- MetaLR 0.03
- MetaSVM -1.12
- CADD 22.60
- PolyPhen-2 0.45
- SIFT 0.09
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available