V18A (p.Val18Ala) variant of NUDT15 (Q9NV35)
V18A (p.Val18Ala) in NUDT15 (Q9NV35) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
V18A (p.Val18Ala) variant details
- p.Val18Ala
- TOPMed rs1434156465
- gnomAD rs1434156465
- Missense
- Variant Prioritization Score for Impact Estimate 0.376
- REVEL 0.25
- MetaLR 0.07
- MetaSVM -1.11
- CADD 24.10
- PolyPhen-2 1.00
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 8.2e-06)
- Structural context available