V16I (p.Val16Ile) variant of NUDT15 (Q9NV35)
V16I (p.Val16Ile) in NUDT15 (Q9NV35) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
V16I (p.Val16Ile) variant details
- p.Val16Ile
- TOPMed rs1023262224
- gnomAD rs1023262224
- Missense
- Variant Prioritization Score for Impact Estimate 0.212
- REVEL 0.10
- MetaLR 0.07
- MetaSVM -1.07
- CADD 14.80
- PolyPhen-2 0.07
- SIFT 0.09
- Most common in the African/African-American population (allele frequency 0.00014)
- Structural context available