V16D (p.Val16Asp) variant of NUDT15 (Q9NV35)
V16D (p.Val16Asp) in NUDT15 (Q9NV35) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
V16D (p.Val16Asp) variant details
- p.Val16Asp
- ExAC rs779488127
- TOPMed rs779488127
- gnomAD rs779488127
- Missense
- Variant Prioritization Score for Impact Estimate 0.454
- REVEL 0.44
- MetaLR 0.27
- MetaSVM -0.17
- CADD 25.50
- PolyPhen-2 0.95
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available