V16A (p.Val16Ala) variant of NUDT15 (Q9NV35)
V16A (p.Val16Ala) in NUDT15 (Q9NV35) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
V16A (p.Val16Ala) variant details
- p.Val16Ala
- ExAC rs779488127
- TOPMed rs779488127
- gnomAD rs779488127
- Missense
- Variant Prioritization Score for Impact Estimate 0.392
- REVEL 0.35
- MetaLR 0.09
- MetaSVM -1.05
- CADD 24.60
- PolyPhen-2 0.69
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available