V14I (p.Val14Ile) variant of NUDT15 (Q9NV35)
V14I (p.Val14Ile) in NUDT15 (Q9NV35) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
V14I (p.Val14Ile) variant details
- p.Val14Ile
- TOPMed rs994248042
- gnomAD rs994248042
- Missense
- Variant Prioritization Score for Impact Estimate 0.267
- REVEL 0.15
- MetaLR 0.09
- MetaSVM -1.11
- CADD 22.20
- PolyPhen-2 0.62
- SIFT 0.23
- Most common in the African/African-American population (allele frequency 7.2e-05)
- Structural context available