V14D (p.Val14Asp) variant of NUDT15 (Q9NV35)
V14D (p.Val14Asp) in NUDT15 (Q9NV35) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
V14D (p.Val14Asp) variant details
- p.Val14Asp
- TOPMed rs1428135695
- Missense
- Variant Prioritization Score for Impact Estimate 0.505
- REVEL 0.44
- MetaLR 0.39
- MetaSVM 0.06
- CADD 27.10
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available