T2K (p.Thr2Lys) variant of NUDT15 (Q9NV35)
T2K (p.Thr2Lys) in NUDT15 (Q9NV35) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
T2K (p.Thr2Lys) variant details
- p.Thr2Lys
- ExAC rs749250312
- TOPMed rs749250312
- gnomAD rs749250312
- Missense
- Variant Prioritization Score for Impact Estimate 0.112
- REVEL 0.07
- MetaLR 0.05
- MetaSVM -1.04
- CADD 6.76
- PolyPhen-2 0.00
- SIFT 0.24
- Population evidence available
- Structural context available