S4T (p.Ser4Thr) variant of NUDT15 (Q9NV35)
S4T (p.Ser4Thr) in NUDT15 (Q9NV35) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
S4T (p.Ser4Thr) variant details
- p.Ser4Thr
- gnomAD rs1484761743
- Missense
- Variant Prioritization Score for Impact Estimate 0.0828
- REVEL 0.03
- MetaLR 0.04
- MetaSVM -1.00
- CADD 4.52
- PolyPhen-2 0.00
- SIFT 0.58
- Most common in the South Asian population (allele frequency 2.5e-05)
- Structural context available