S4N (p.Ser4Asn) variant of NUDT15 (Q9NV35)
S4N (p.Ser4Asn) in NUDT15 (Q9NV35) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
S4N (p.Ser4Asn) variant details
- p.Ser4Asn
- gnomAD rs1484761743
- Missense
- Variant Prioritization Score for Impact Estimate 0.0754
- REVEL 0.01
- MetaLR 0.03
- MetaSVM -0.99
- CADD 4.29
- PolyPhen-2 0.00
- SIFT 0.65
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available