S37W (p.Ser37Trp) variant of NUDT15 (Q9NV35)
S37W (p.Ser37Trp) in NUDT15 (Q9NV35) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
S37W (p.Ser37Trp) variant details
- p.Ser37Trp
- ExAC rs778722701
- TOPMed rs778722701
- gnomAD rs778722701
- Missense
- Variant Prioritization Score for Impact Estimate 0.245
- REVEL 0.05
- MetaLR 0.07
- MetaSVM -1.09
- CADD 23.20
- PolyPhen-2 0.92
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 5.9e-05)
- Structural context available