S37L (p.Ser37Leu) variant of NUDT15 (Q9NV35)
S37L (p.Ser37Leu) in NUDT15 (Q9NV35) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
S37L (p.Ser37Leu) variant details
- p.Ser37Leu
- ExAC rs778722701
- TOPMed rs778722701
- gnomAD rs778722701
- Missense
- Variant Prioritization Score for Impact Estimate 0.238
- REVEL 0.07
- MetaLR 0.03
- MetaSVM -1.04
- CADD 19.50
- PolyPhen-2 0.01
- SIFT 0.08
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available