R11P (p.Arg11Pro) variant of NUDT15 (Q9NV35)
R11P (p.Arg11Pro) in NUDT15 (Q9NV35) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
R11P (p.Arg11Pro) variant details
- p.Arg11Pro
- ExAC rs764632714
- TOPMed rs764632714
- gnomAD rs764632714
- Missense
- Variant Prioritization Score for Impact Estimate 0.491
- REVEL 0.37
- MetaLR 0.10
- MetaSVM -1.01
- CADD 26.80
- PolyPhen-2 0.96
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available