R11G (p.Arg11Gly) variant of NUDT15 (Q9NV35)
R11G (p.Arg11Gly) in NUDT15 (Q9NV35) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
R11G (p.Arg11Gly) variant details
- p.Arg11Gly
- Ensembl rs2137793966
- Missense
- Variant Prioritization Score for Impact Estimate 0.35
- REVEL 0.29
- MetaLR 0.13
- MetaSVM -0.82
- CADD 24.50
- SIFT 0.00
- Most common in the HGDP:LAHU population (allele frequency 0.1)
- Structural context available