R10W (p.Arg10Trp) variant of NUDT15 (Q9NV35)
R10W (p.Arg10Trp) in NUDT15 (Q9NV35) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
R10W (p.Arg10Trp) variant details
- p.Arg10Trp
- ExAC rs775629796
- TOPMed rs775629796
- gnomAD rs775629796
- Missense
- Variant Prioritization Score for Impact Estimate 0.133
- REVEL 0.02
- MetaLR 0.02
- MetaSVM -1.02
- CADD 14.20
- PolyPhen-2 0.20
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available