Q6E (p.Gln6Glu) variant of NUDT15 (Q9NV35)
Q6E (p.Gln6Glu) in NUDT15 (Q9NV35) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
Q6E (p.Gln6Glu) variant details
- p.Gln6Glu
- ExAC rs776779121
- gnomAD rs776779121
- Missense
- Variant Prioritization Score for Impact Estimate 0.195
- REVEL 0.13
- MetaLR 0.02
- MetaSVM -1.06
- CADD 2.75
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the East Asian population (allele frequency 2.6e-05)
- Structural context available