P7S (p.Pro7Ser) variant of NUDT15 (Q9NV35)
P7S (p.Pro7Ser) in NUDT15 (Q9NV35) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
P7S (p.Pro7Ser) variant details
- p.Pro7Ser
- TOPMed rs1240232167
- gnomAD rs1240232167
- Missense
- Variant Prioritization Score for Impact Estimate 0.103
- REVEL 0.09
- MetaLR 0.07
- MetaSVM -1.01
- CADD 1.05
- PolyPhen-2 0.00
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available