P7L (p.Pro7Leu) variant of NUDT15 (Q9NV35)
P7L (p.Pro7Leu) in NUDT15 (Q9NV35) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
P7L (p.Pro7Leu) variant details
- p.Pro7Leu
- Ensembl rs2137793892
- Missense
- Variant Prioritization Score for Impact Estimate 0.098
- REVEL 0.06
- MetaLR 0.05
- MetaSVM -1.04
- CADD 5.37
- PolyPhen-2 0.00
- SIFT 0.08
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available