P26S (p.Pro26Ser) variant of NUDT15 (Q9NV35)
P26S (p.Pro26Ser) in NUDT15 (Q9NV35) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
P26S (p.Pro26Ser) variant details
- p.Pro26Ser
- gnomAD 13-48037822-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.388
- REVEL 0.18
- MetaLR 0.07
- MetaSVM -1.08
- CADD 23.30
- PolyPhen-2 0.91
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available
- Literature evidence available