P26A (p.Pro26Ala) variant of NUDT15 (Q9NV35)
P26A (p.Pro26Ala) in NUDT15 (Q9NV35) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
P26A (p.Pro26Ala) variant details
- p.Pro26Ala
- ExAC rs561923692
- TOPMed rs561923692
- gnomAD rs561923692
- Missense
- Variant Prioritization Score for Impact Estimate 0.397
- REVEL 0.20
- MetaLR 0.06
- MetaSVM -1.10
- CADD 23.90
- PolyPhen-2 0.91
- SIFT 0.04
- Most common in the Middle Eastern population (allele frequency 0.00044)
- Structural context available