L31V (p.Leu31Val) variant of NUDT15 (Q9NV35)
L31V (p.Leu31Val) in NUDT15 (Q9NV35) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
L31V (p.Leu31Val) variant details
- p.Leu31Val
- TOPMed rs752857256
- Missense
- Variant Prioritization Score for Impact Estimate 0.205
- REVEL 0.13
- MetaLR 0.08
- MetaSVM -1.11
- CADD 19.80
- PolyPhen-2 0.49
- SIFT 0.15
- Most common in the Non-Finnish European population (allele frequency 5.4e-06)
- Structural context available