K33T (p.Lys33Thr) variant of NUDT15 (Q9NV35)
K33T (p.Lys33Thr) in NUDT15 (Q9NV35) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
K33T (p.Lys33Thr) variant details
- p.Lys33Thr
- gnomAD 13-48037844-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.296
- REVEL 0.21
- MetaLR 0.08
- MetaSVM -1.10
- CADD 22.90
- PolyPhen-2 0.95
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available