K33N (p.Lys33Asn) variant of NUDT15 (Q9NV35)
K33N (p.Lys33Asn) in NUDT15 (Q9NV35) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
K33N (p.Lys33Asn) variant details
- p.Lys33Asn
- 1000Genomes rs150241065
- ESP rs150241065
- ExAC rs150241065
- TOPMed rs150241065
- Missense
- Variant Prioritization Score for Impact Estimate 0.254
- REVEL 0.21
- MetaLR 0.07
- MetaSVM -1.13
- CADD 23.90
- PolyPhen-2 0.96
- SIFT 0.01
- Most common in the South Asian population (allele frequency 3.6e-05)
- Structural context available