K24R (p.Lys24Arg) variant of NUDT15 (Q9NV35)
K24R (p.Lys24Arg) in NUDT15 (Q9NV35) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
K24R (p.Lys24Arg) variant details
- p.Lys24Arg
- TOPMed rs1003070511
- Missense
- Variant Prioritization Score for Impact Estimate 0.0722
- REVEL 0.01
- MetaLR 0.01
- MetaSVM -0.92
- CADD 3.61
- PolyPhen-2 0.00
- SIFT 0.58
- Most common in the Non-Finnish European population (allele frequency 4.5e-06)
- Structural context available