K24N (p.Lys24Asn) variant of NUDT15 (Q9NV35)
K24N (p.Lys24Asn) in NUDT15 (Q9NV35) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
K24N (p.Lys24Asn) variant details
- p.Lys24Asn
- 1000Genomes rs549709884
- ExAC rs549709884
- TOPMed rs549709884
- gnomAD rs549709884
- Missense
- Variant Prioritization Score for Impact Estimate 0.104
- REVEL 0.06
- MetaLR 0.02
- MetaSVM -0.93
- CADD 8.18
- PolyPhen-2 0.00
- SIFT 0.46
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available