G36R (p.Gly36Arg) variant of NUDT15 (Q9NV35)
G36R (p.Gly36Arg) in NUDT15 (Q9NV35) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
G36R (p.Gly36Arg) variant details
- p.Gly36Arg
- ExAC rs753319151
- TOPMed rs753319151
- gnomAD rs753319151
- Missense
- Variant Prioritization Score for Impact Estimate 0.346
- REVEL 0.17
- MetaLR 0.04
- MetaSVM -1.14
- CADD 25.30
- PolyPhen-2 0.78
- SIFT 0.01
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available