G36D (p.Gly36Asp) variant of NUDT15 (Q9NV35)
G36D (p.Gly36Asp) in NUDT15 (Q9NV35) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
G36D (p.Gly36Asp) variant details
- p.Gly36Asp
- gnomAD 13-48037853-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.364
- REVEL 0.17
- MetaLR 0.02
- MetaSVM -1.01
- CADD 22.40
- PolyPhen-2 0.11
- SIFT 0.02
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available