G17R (p.Gly17Arg) variant of NUDT15 (Q9NV35)
G17R (p.Gly17Arg) in NUDT15 (Q9NV35) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data and structural context.
G17R (p.Gly17Arg) variant details
- p.Gly17Arg
- Ensembl rs1950543785
- Missense
- Variant Prioritization Score for Impact Estimate 0.558
- REVEL 0.58
- MetaLR 0.11
- MetaSVM -1.01
- CADD 25.00
- PolyPhen-2 1.00
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available