G15A (p.Gly15Ala) variant of NUDT15 (Q9NV35)
G15A (p.Gly15Ala) in NUDT15 (Q9NV35) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
G15A (p.Gly15Ala) variant details
- p.Gly15Ala
- gnomAD rs1345971588
- Missense
- Variant Prioritization Score for Impact Estimate 0.341
- REVEL 0.19
- MetaLR 0.04
- MetaSVM -1.12
- CADD 21.60
- PolyPhen-2 0.14
- SIFT 0.01
- Most common in the East Asian population (allele frequency 2.6e-05)
- Structural context available