G13R (p.Gly13Arg) variant of NUDT15 (Q9NV35)
G13R (p.Gly13Arg) in NUDT15 (Q9NV35) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
G13R (p.Gly13Arg) variant details
- p.Gly13Arg
- ExAC rs767290343
- TOPMed rs767290343
- gnomAD rs767290343
- Missense
- Variant Prioritization Score for Impact Estimate 0.467
- REVEL 0.34
- MetaLR 0.08
- MetaSVM -1.02
- CADD 24.10
- PolyPhen-2 1.00
- SIFT 0.42
- Most common in the Non-Finnish European population (allele frequency 3e-05)
- Structural context available