Y25H (p.Tyr25His) variant of NTRK3 (NT-3 growth factor receptor)
Y25H (p.Tyr25His) in NTRK3 (NT-3 growth factor receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
Y25H (p.Tyr25His) variant details
- p.Tyr25His
- gnomAD rs1006732882
- Missense
- Variant Prioritization Score for Impact Estimate 0.3
- REVEL 0.20
- CADD 24.20
- PolyPhen-2 0.99
- SIFT 0.37
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available