W13C (p.Trp13Cys) variant of NTRK3 (NT-3 growth factor receptor)
W13C (p.Trp13Cys) in NTRK3 (NT-3 growth factor receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
W13C (p.Trp13Cys) variant details
- p.Trp13Cys
- gnomAD rs1456468651
- Missense
- Variant Prioritization Score for Impact Estimate 0.604
- REVEL 0.59
- CADD 26.70
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available