T81S (p.Thr81Ser) variant of NTRK3 (NT-3 growth factor receptor)
T81S (p.Thr81Ser) in NTRK3 (NT-3 growth factor receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
T81S (p.Thr81Ser) variant details
- p.Thr81Ser
- TOPMed rs1178373735
- gnomAD rs1178373735
- Missense
- Variant Prioritization Score for Impact Estimate 0.353
- REVEL 0.28
- CADD 21.70
- PolyPhen-2 0.02
- SIFT 0.07
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available